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Parkinson's plus syndromes: Symptoms, causes, and treatments

Key takeawaysParkinson’s plus syndromes are a group of neurological disorders that are similar to Parkinson’s disease but have a different disease progression and slightly different symptoms.Parkinson’s plus syndromes include progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and dementia with Lewy bodies (DLB).Treatments focus on managing symptoms through medications, physical therapy, speech therapy, and occupational therapy to improve the pat...
MD/Alert •

Pembrolizumab Increases Response Rates but Not Survival in Resectable Locally Advanced G/GEJ Adenocarcinoma

Perioperative pembrolizumab plus chemotherapy increased pathologic complete response (pathCR) rates in resectable gastric and gastroesophageal junction (G/GEJ) adenocarcinoma, but did not achieve statistically significant improvements in event-free survival (EFS) and overall survival (OS) at final analysis of the phase 3 KEYNOTE-585 trial, results of which were published in the Journal of Clinical Oncology.
MD/Alert •

Azelastine Nasal Spray Reduces SARS-CoV-2 Infections by 67% in Randomized Trial

Azelastine nasal spray significantly reduced SARS-CoV-2 infections by 67% compared with placebo in healthy adults, suggesting a potential prophylactic approach for COVID-19 prevention, according to a study published in JAMA Internal Medicine.

"These findings support the potential of azelastine as a safe prophylactic approach warranting confirmation in larger, multicentric trials," Thorsten Lehr, PhD, professor at Saarland University, Saarbrücken, Germany, and colleagues wrote.

Ways to declutter: Tips, benefits, and more

Excess clutter in living spaces can contribute to stress and issues with mental health. Understanding how to declutter can provide significant mental and physical health benefits.Decluttering involves removing unnecessary items to create a more organized, functional environment. Research suggests that cluttered spaces can increase stress levels, reduce productivity, and negatively impact the quality of life.By systematically removing excess possessions, people can create healthier living spaces...
Medical News Today •

Tamarind: Benefits, uses, and more

Tamarind is a tropical fruit that offers several potential health benefits due to its rich nutrient content and bioactive compounds. Tamarind contains vitamins, minerals, antioxidants, and fiber. It is a food ingredient and a traditional remedy for various health conditions. The fruit’s sweet-sour taste makes it popular in cuisines, while its natural compounds have attracted scientific interest for potential therapeutic applications.
Medical News Today •

Retinol vs. tretinoin: Differences, uses, and more

Retinol and tretinoin are forms of vitamin A used in skin care for their aging support and acne-fighting properties. Retinol and tretinoin share similar origins and some overlapping benefits. However, they differ substantially in their strength, availability, and how they work on the skin. These compounds work through similar mechanisms, promoting cell turnover, stimulating collagen production, and addressing fine lines, acne, and hyperpigmentation.
Medical News Today •

Food aversion: Signs, treatment, and more.

“I always hated chocolate growing up. The one time I tasted it, it was medicinal. It was an experience that left an impression on me. From that point on, everything was unpleasant about chocolate, including the color and the smell. With all the celebrations and holidays, I never touched chocolate. The kids in my family always chose a chocolate cake for their birthdays. Instead of the appeal, simply being close enough to a chocolate cake made me nauseous.
Medical News Today •

Face yoga: Benefits, exercises, and more

Face yoga involves a series of facial exercises designed to engage the muscles in the face and neck. It may improve the structural appearance of the face, but evidence is unclear. Face yoga employs targeted exercises and massage techniques designed to tone facial muscles and potentially improve skin appearance. It is a noninvasive approach that has gained popularity with people seeking alternatives to cosmetic procedures for maintaining youthful-looking skin.
Medical News Today •

HYROX: Benefits, risks, and more

“HYROX is quite an intense form of exercise. Like all exercise, it improves fitness and challenges the body with a strong stimulus. I like HYROX because it allows you to condense a significant amount of exercise into a short period of time. I can fit in a condensed HYROX session during my lunch break at work, providing a good variety of exercise as it’s a full-body workout. It is measurable, so you can see how you improve as each stage is timed, giving the feeling of progress.
Medical News Today •

The role of Fusobacterium colorectal cancer

Fusobacterium nucleatum is a bacterium that usually lives in the mouth. However, it can migrate to the colon, where it fuels the growth and progression of Fusobacterium colorectal cancer. The presence of specific bacteria within colon tumors appears to affect cancer biology, influencing how tumors develop, grow, and respond to treatment. The discovery has opened new avenues for understanding why some colon cancers behave more aggressively than others.
Medical News Today •

Hoarding OCD: What to know

Individuals who experience hoarding related to OCD may have distressing feelings about discarding items. It can drive compulsive saving behaviors that they recognize as excessive. Obsessive-compulsive disorder (OCD) involves recurring, unwanted thoughts or obsessions that drive repetitive behaviors or mental acts or compulsions, in an attempt to reduce distress. Mental health professionals’ understanding of OCD has changed significantly over time.
Medical News Today •

Schizophrenia and aggressive behaviour toward family members

In schizophrenia, aggression toward family can occur. This complex mental health condition can result in hostile behavior during periods of acute symptoms. While aggression is not inevitable for individuals with schizophrenia, it can occur, particularly during acute episodes or if poorly managed. This behavior can be frightening and overwhelming for families who want to provide support while ensuring everyone’s safety.
Medical News Today •

Treatment-resistant OCD: Causes, management, and more

Treatment-resistant OCD occurs when standard therapies do not provide adequate relief from obsessive-compulsive symptoms. While many people with obsessive-compulsive disorder (OCD) improve significantly with therapy and medication, some do not experience symptom relief. This resistance can be frustrating and discouraging for individuals who have tried multiple treatments without success. Treatment-resistant or refractory OCD may develop for various reasons.
Medical News Today •

Understanding the link between PTSD and anger

I was diagnosed with PTSD after a life-altering accident when I was hit by a car driven by one of my colleagues while crossing a road on my way home from work. In an instant, everything changed. I was hospitalized with physical injuries, but the emotional impact surfaced later, culminating in a PTSD diagnosis. What surprised me most was the anger I felt – not toward the driver, but toward my own body. I was desperate to recover and return to my life, but my body couldn’t keep up.
Medical News Today •

Carcinoma of unknown primary: Treatment and survival

Carcinomas are cancers that start in epithelial cells, which line organs, skin, and blood vessels. Carcinoma of unknown primary (CUP) means doctors can detect this cancer, but they cannot identify where it began. Doctors make a diagnosis of CUP when cancer has already spread to other parts of the body. It is a challenging condition to treat, and receiving the diagnosis can be hard on people and their loved ones.
Medical News Today •

What happens to the body when you stop drinking alcohol?

“In the first week, I didn’t realize how much energy alcohol was stealing from me, emotionally and physically. In the first month, the brain fog started to lift. I could feel my intuition coming back online. One year later, I began to see that alcohol was just the tip of the iceberg. Underneath it all was a deeper compulsion, to chaos, to love, to self-abandonment. At first, quitting was for health. I was prescribed a medication that meant I had to stop drinking for a while.
Medical News Today •

Checking OCD: Signs, treatment, and more

“My checking OCD has revolved around intrusive thoughts related to my safety and the safety of my loved ones. Initially, it revolved around an intrusive thought that someone was going to break into my home at night and harm my family and me, so before going to bed, I would repeatedly check if my front door was locked. Eventually, it progressed to checking if all the windows in my house were also closed. After checking, I would doubt that I checked correctly, and have to do it all over again.
Integrity Locums •

How Health Systems Are Leveraging Locum Tenens in 2025 - Integrity Locums

The days of viewing locum tenens as only emergency staffing for unexpected departures are over. Forward-thinking healthcare executives have discovered that purposeful temporary clinician deployment can drive innovation, manage costs, and accelerate growth in ways permanent staffing simply can’t match.

While many health systems still use locums reactively to fill sudden gaps, the most successful networks leverage temporary practitioners as business assets.
Medical News Today •

31 types of medical doctors: A guide to medical specialists

There are many types of medical doctors, each specializing in specific areas of health and medicine. The medical field includes many types of doctors, from primary care physicians providing general healthcare to cardiologists treating heart conditions, dermatologists managing skin disorders, and surgeons performing operations. Medical specialization developed as knowledge became too complex for one doctor to master everything.
Integrity Locums •

Working Locums While Raising a Family - Integrity Locums

Thousands of physicians and advanced practice providers (APPs) successfully balance locum careers while raising a family and with rich personal lives. From pediatricians who never miss a school play to emergency medicine physicians who coach Little League, today’s locum marketplace offers flexibility that can enhance relationships, not strain them.

The key lies in strategic planning and intentional choices.
Medical News Today •

Coming out to your doctor: Advice and more

Although disclosure is voluntary, being open about sexual orientation and gender identity could enhance the quality of medical care received. Coming out to a healthcare professional can feel daunting, but sharing information about sexual orientation and gender identity could improve the quality of care. Many LGBTQIA+ individuals wonder whether they need to disclose this personal information during medical appointments. The decision to come out to a doctor is deeply personal.
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